author(s)
Ankit Nagar, Rajeev Ranjan Kumar and Stuti Vatsya

abstract
Theileria annulata is an important tick-borne haemoprotozoan disease affecting dairy animals in tropical and subtropical region of the country and is responsible for causing huge economic losses to the dairy farmers. The present study was undertaken to evaluate the efficacy of buparvaquone, chloroquine, α, β-artether and diminazine aceturate along with oxytetracycline in cattle naturally infected with T. annulata. Animals of GI, GII, GIII and GIV of 10 animals each were treated with single dose of buparvaquone @ 2.5mg/kg body weight, chloroquine @ 1ml/30kg body weight, α,β-artether @1ml/30kg body weight and diminazine aceturate @ 3.5mg/kg body weight, respectively along with intravenous injection of oxytetracycline @ 20ml/kg body weight for 5 days. The reduction in intensity of infection from ++++ to +, ++++ to ++, ++++ to ++ and ++++ to ++ was recorded in animals of GI, GII, GIII and GIV, respectively. Thus, buparvaquone showed better efficacy than other drugs used in the present study.