author(s)
Tasok Leya, Ram Prakash Raman and Prem Prakash Srivastava

abstract
The aim of the current study was to evaluate the effect of CSD on haematological parameters of Cirrhinus mrigala fingerlings fed on four CSD viz: T1 (0.25%), T2 (0.5%), T3 (1.0%), T4 (1.5%), and a control group (0% curcumin level), and the experimental was carried for 45 days. The sampling was done by taking blood on 0, 15, 30, and 45 days interval from different treatment groups. After 45 days of the experimental period, fifteen fishes from each replicate were challenged with virulent Edwardsiella tarda. Mortality was recorded up to 14 days post challenged. The experimental results showed that there was a significant (p>0.05) difference in all treatment group in all haematological parameters in compared to control group. However, among treatment groups there was insignificant differences was observed in haematological parameters. The mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) showed no significant (p>0.05) difference among the treatment group. Total erythrocyte count (TEC) and haemoglobin (Hb) was, also not significantly difference in all treatment group. However, total leukocyte count (TLC) was significantly (p>0.05) different among the treatment groups. The high values were observed in T4 followed by T3, T2, and T1, respectively. Dietary supplement curcumin at 1.5% (T4) showed significantly (p<0.05) higher percentage survival (80%) against Edwardsiella tarda challenged than control. Thus, the study has concluded that curcumin supplement diet fed to fish showed no any significant difference among treatments but it improves the immunity of the fish because of an increase in TLC.