The present clinical study was carried out in Kamrup district of Assam under Tribal Sub Plan (TSP) Project. Twelve Assam Hill Goats showing clinical signs of rumen acidosis were selected for the trial. The results revealed that the ruminal pH, ruminal motility, odour, colour, consistency of rumen liquor, ruminal microflora and protozoal motility were differed from healthy goats. Haematological parameters showed increased haemoglobin, packed cell volume and total leukocyte counts. Biochemical examination showed increased blood lactic acid level, blood glucose level, total protein, AST, ALT, BUN and creatinine level. The animals were treated with sodium bicarbonate solution intravenously (7.5% w/v) @ 1 ml/kg body weight mixed with normal saline solution, Pheneramine maleate Injection intramuscularly @ 0.5 mg/kg body weight, Injection Vitamin B-complex intramuscularly, Rumenotoric bolus (Rumentus) and powder Bufzone orally @ 50g once a day until recovery. The clinical signs were gradually disappeared after treatment.