A male dog of 5 year showed history of anorexia, vomiting, drowsy and a normal body temperature. It was tentatively diagnosed the case of renal failure. And for diagnosis owner was advised for test and report revealed that PLT was low. BUN and Creatinine was higher from the normal range. Owner was advised for fluid therapy with ringer lactate 500ml, ranitidine 1 ml and eldervet i.e multivitamin. Ondansetron was advised if vomiting occur.