author(s)
Tandale RU, Moregaonkar SD, Gangane GR, Dhumal MV, Deshpande AR, Ghorpade PB and Chavan PA

abstract
120, day old broiler chicks were randomly divided into 6 equal groups. Chicks from group II, III, IV and V were challenged with single oral dose of E. coli broth culture @ 0.3-0.5 ml (1x10⁹CFU/ml). Chicks from group III were fed with curry leaves powder @ 1% of feed. However, chicks from group IV and V were given with leofloxacin @ 1gm/10kg body weight orally and leofloxacin (1gm/10kg B.W.) plus curry leaves powder (1% of feed), respectively. Hematological and biochemical parameters were recorded on 0^th, 7^th, 14^th and 21^st day post infection interval. Significant decrease in mean values of Hb, PCV, TEC, lymphocytes, total protein, albumin and globulin, whereas, significant increase in TLC, heterophil, creatinine, AST and ALT were observed in birds of group II at 7^th and 14^th day post infection intervals of study. Birds infected with E. coli and treated with curry leaves powder showed partial improvement in altered values of all hematological and biochemical parameters at 7^th and 14^th day intervals of study. Combined treatment of curry leaves powder and leofloxacin in E. coli infected birds showed better ameliorative effect on all hemto-biochemical parameters than individual treatment at 7^th and 14^th day post infection intervals of study.