author(s)
Amit Baranwal, NP Singh, Ashok Kumar, Avneesh Kumar, PK Upadhyaya and AK Srivastava

abstract
Colibacillosis, an acute, infectious and mostly systemic disease resulting in significant economic losses, is being increasingly detected among poultry flocks worldwide. The present study aimed to supply documented information on the epidemiological and economic effects of the disease to oblige in disease control policies and planning research preference in the poultry sector. The clinical signs respiratory distress, reduced appetite; poor growth and mortality were evident. The morbid chicks were examined for postmortem changes and gross lesionsinclude cheesy deposition over heart and liver, pericarditis, highly congested and septicemia liver, perihepatitis and airsacculitis. The chicks were treated with levofloxacin (10%) antibiotic (@ 1 gram/Liter of water for 3 days) and found to be effective against Escherichia coli infection in broilers. General hygienic and bio-security measures should be part of the overall management plan of poultry farms for effective control of bacterial infection.