Therapeutic management of canine babesiosis associated with acute renal failure
Dr. Kamal Hasan, Dr. Manjunatha DR, Dr. Ramesh D, Dr. Satheesha SP and Dr. Shivakumar M
Canine babesiosis has worldwide significance caused by several Babesia spp. which readily parasitize red blood cells and causes progressive anemia associated with high morbidity and mortality. The disease onset is often acute with affected dogs suffering from fever and lethargy and thereafter may display clinical manifestations of anaemia, liver, kidney dysfunction, and haemostatic abnormalities. Five cases of different breeds of canine presented to Teaching Veterinary Clinical Complex Hospital, Hassan during the month of August 2018 to January 2019 with the history of Anorexia, High fever with vomiting in greenish colour and low platelet count which had not been responding to any treatment. Diagnosis was confirmed for Babesia canis on microscopic examination. Serum analysis revealed elevated serum creatinine levels above 1.2 mg/dl is an indicative of renal failure. The animals were treated with imidocarb dipropionate at the rate of 6.6 mg /kg Body weight, once in a week for two weeks. Clindamycin was given at the rate of 11 mg/kg Body weight orally along with blood transfusion as supportive therapy. In addition, Erythropoietin injection was given to the all animals at the rate of 100 I.U /Kg Body weight intravenously thrice in a week for 4 weeks. Phosphate binders such as calcium acetate (Ipakatine ®, Vetoquinol) 30 gram twice daily for one month.The combination of Imidocarb dipropionate, clindamycin along with Blood transfusion as supportive therapy yielded in effective treatment of Canine Babesiosis.
Dr. Kamal Hasan, Dr. Manjunatha DR, Dr. Ramesh D, Dr. Satheesha SP, Dr. Shivakumar M. Therapeutic management of canine babesiosis associated with acute renal failure. J Entomol Zool Stud 2019;7(4):552-555.