author(s)
Ankur Upadhyay, Mukesh Srivastava, Ashish Srivastava, Arvind Tripathi, PN Panigrahi, Amangeet Parashar, Jaideep Singh, Vimlesh Kumar and Shivani Rajoriya

abstract
Present study describes the haemato-biochemical analysis of dogs affected with sarcoptic mange and its treatment using doramectin. Study was undertaken on six client owned dogs confirmed to be suffering from sarcoptic mange irrespective of age, sex and breed presented at TVCC DUVASU, Mathura, while six healthy dogs were taken as control. There was significantly higher concentration of haematological parameters viz. total leucocyte count, eosinophil counts, mean corpuscular volume in scabetic dogs than respective control animals. On contrary mean concentration of haemoglobin, total erythrocyte count, haematocrit, lymphocyte counts decreased significantly in scabetic dogs than respective control animals. The biochemical parameters revealed significantly higher concentration of aspartate aminotransferase and alanine aminotransferase (30.14±0.60 µ/L vs 21.49±1.20 µ/L, 38.01±1.02 µ/L vs 28.33±3.72 µ/L; respectively) in scabetic dogs than in control while significant lower concentration of glucose, cholesterol, total protein and albumin in scabetic dogs than in control (46.83±1.57 mg/dL vs 70.33±3.16 mg/dL, 164.50±5.15 mg/dL vs 222.83±11.89 mg/dL, 4.46±0.11 gm/dL vs 6.06±0.06 gm/dL and 1.70±0.06 gm/dL vs 3.21±0.06 gm/dL; respectively). Cases were efficiently managed by using subcutaneous injections of doramectin @ 0.4 mg/kg body weight subcutaneously at weekly intervals along with standard treatment of pyoderma.