author(s)
Hussain Ahmed, Meerwais Khan, Hameed Ur Rehman, Hazrat Noor, Nasir Ali Khan,Munir Ahmed Khan. Javeed Ahmad Sheikh and Wisal Ahmad

abstract
Cutaneous Leishmaniasis is a neglected major disease generally in the world and especially in the Eastern Mediterranean region where 57% of its cases occurs. It is particularly present in rural areas of Pakistan. It is known by different local names such as Delhi boil in India, Saldana in Afghanistan and kaal daana in Pakistan. It is caused by single-celled protozoan known as Leishmania. In Pakistan, it is caused either by Leishmania tropica or Leishmania major. It is called Anthroponotic and zoonotic in former and later cases respectively. It is transmitted from one vertebrate host to another vertebrate host by a female sandfly of genera Phlebotomus and Lutzomyia in Pakistan. It has diverse clinical manifestation, however, the skin lesion which appears due to the infection of this diseases have some common clinical features. Size, location, number and type of lesion in cutaneous Leishmaniasis varies. Different factors like migration, socioeconomic factors, climate change contribute to the developing of this disease.