Theileriosis is a major tick haemoprotozoan disease in cattle, buffalo, sheep, goat and horses as well as wild ruminant animals However, indigenous cattle (Boss indicus) are less affected by Theileriosis than crossbred cattle. Among the various tick born haemoprotozoan disease, bovine tropical Theileriosis caused by Theileria annulata and transmitted by Hyalomma anatolicum anatolicum ticks species, results in lethal infections and considerable high mortality in crossbred cattle then the Zebu cattle. Once infected the animals remain carrier for life time, since the organisms hide in macrophage and lymphoid tissue. The compromises the immune system and the animal are prone to a number of super infections. 5 clinical cases of Theileriosis in calves recorded at Veterinary Clinical Complex, Post Graduate Institute of Veterinary Education & Research, Jaipur (Raj.) during October, 2018 to November, 2018. Clinically, fever, tachycardia, polypnea, reduced appetite, dullness or emaciated body condition with rough hair coat (Presence of ticks on skin or hair coat), pale to icterus to whitish mucous membrane and enlargement of both lymph node (Parotid and Prescapular lymph node) was observed. The cases were diagnosed on the basis of clinical findings, laboratory investigation and blood smear examination. Treatment with combination therapy of Buparvaquone and oxytetracycline along with haematinics and multivitamins and advised of beet feeding were found effective against bovine Theileriosis.