author(s)
Nileshkumar Pagrut, Subha Ganguly, Shashi Tekam, Rinku Pendharkar and Neelam Kumari Faran

abstract
In the present study lead induced histological alterations in mice studied. The male mice were divided into 3 groups and treated as follows: Group 1: healthy control and Group II with 0.4 and Group III with 1.2 mg/kg body weight of doses of lead acetate respectively in their daily supply of drinking water for twelve weeks. It was observed that there was a significant decline in the the total erythrocyte count (TEC) following exposure of lead acetate in group II and III in comparison with the control group. It was also observed marked decrease in the levels of haemoglobin (Hb) and packed cell volume (PCV). MCV, MCH, and MCHC were also significantly reduced in treated mice relative to the healthy ones.