author(s)
Papori Bora, Pranati Das, Pritam Mohan and Anurag Borthakur

abstract
This study was conducted to evaluate the impact of supplementation of proso millet based diet on high fat diet (HFD) induced hyperlipidemia in rats. A total of 48 numbers of healthy wister rats of either sex weighing between 120-200 g were selected for the study. After a period of acclimatization (1 week), the rats were randomly segregated into 8 different groups, each group having a total of 6 rats. Group I was as normal control fed a standard basal diet and Group II as treated control was fed a HFD containing 20% coconut oil. Group III, IV, and V were fed a HFD containing 10%, 20% and 40% whole grain (with husk) proso millet flour, respectively. Group VI, VII and VIII were fed HFD containing 10%, 20% and 40% dehusked (unpolished) proso millet flour, respectively. All animals had ad libitum access to food and water throughout the experiment. Results showed significant improvements in plasma high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, total cholesterol and triglycerides level in the groups supplemented with proso millets based diet as compared to the group fed HFD alone. Thus, it can be inferred that the proso millet is efficacious in lowering cholesterol levels in rats.